According to a recent study published by Canadian pharmacologists, the consumption of grapefruit and grapefruit juice combined with certain drugs could turn out to be deadly.
The study has been carried out by Canadian scientists and according to the discoveries, consumers could be exposed to the intake of certain ingredients that could lead to adverse reactions like respiratory and kidney failure as well as gastric bleeding.
Scientists have indicated that twenty-six new drugs could pose a risk to patients if mixed with grapefruit in the patient’s system. According to a pharmacologist at the Lawson Health Institute Research Center in Ontario, 13 drugs could lead to the death of patients if mixed with grapefruit. The issue, researchers report, is linked to the presence of organic chemical compounds called furanocoumarins in these fruits, which have an impact on the human digestive enzyme. This could have a negative impact on the consumption of certain drugs due to the fact that this enzyme helps the organism to metabolize toxic substances. In a healthy organism, the enzyme keeps the toxic ingredients from getting into the bloodstream. When doctors know patients drink grapefruit regularly, drug prescriptions are adjusted.
The reason for that is that when that enzyme is affected and inhibited by the grapefruit intake, drugs could become concentrated in the patient’s system, leading to the increase in dosage of the medication in the patient’s body. The danger, scientists point out, is that neither patients nor doctors believe this threat is real.
According to the study, drinking less than a cup of the grapefruit juice a day for a three-day period could lead to a 330 percent increase of the concentration of simvastatin. Regardless of when the juice is consumed, as soon as the ingredient is absorbed by the organism, the enzyme is inhibited, scientists say.
Research says that more than 85 drugs can have a negative impact in the organism once the ingredients interact with grapefruit, grapefruit juice or concentrate. Patients using Multaq, which is a heart drug, poses a serious risk to patients if taken when the patient consumes grapefruit.
Scientists report that it’s still unknown how many people have been harmed by using drugs that interact poorly with grapefruit. Scientists say that the side effects are not recognized right away. People who are older than 45-years-old consume grapefruit juice more often while also taking drugs, which makes this age group prone to being affected.
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